Bermans J. Iskandar — Curriculum Vitae

Title
Professor of Neurosurgery and Pediatrics, 2010-present
Director of Pediatric Neurosurgery
University of Wisconsin Hospital and Clinics and
UW Children’s Hospital

Address
Department of Neurological Surgery
University of Wisconsin Medical School
K4/832 Clinical Science Center
600 Highland Avenue
Madison, WI 53792–3232

Other UW Responsibilities
Staff surgeon, Meriter Hospital
Staff surgeon, William S. Middleton VA Hospital
Director, CNS Regeneration Laboratory
Co-director, Multidisciplinary Brachial Plexus Clinic

Education
  American University of Beirut
Biology
September 1981 – June 1982
BA California State University at Northridge
Summa cum laude in Cell and Molecular Biology
September 1982 – June 1985
MD University of Pennsylvania School of Medicine September 1985 – June 1989

Post-Graduate Work

Intern
Department of General Surgery
Boston University Medical Center

Resident and Chief Resident
Division of Neurosurgery
Duke University Medical Center

Fellow in Pediatric Neurosurgery
Division of Pediatric Neurosurgery
The Children’s Hospital
Birmingham, Alabama

Assistant Professor of Neurosurgery and Pediatrics
University of Wisconsin Hospital and Clinics and
UW Children’s Hospital
Madison, WI

Associate Professor of Neurosurgery and Pediatrics
Director of Pediatric Neurosurgery
University of Wisconsin School of Medicine and Public Health
Madison, WI

Associate Professor of Neurosurgery and Pediatrics, with Tenure
Director of Pediatric Neurosurgery
University of Wisconsin School of Medicine and Public Health
Madison, WI

July 1989 – June 1990



July 1990 – June 1996



July 1996 – June 1997




July 1997 – February 2003

 


2003-2007

 


2007-2010


Previous Employment
Assistant Professor of Neurosurgery and Pediatrics
University of Wisconsin Hospital and Clinics and UW Children’s Hospital
Madison, WI
July 1997-February 2003

Research Positions
Research Associate
Department of Neurobiology
Duke University Medical Center
Project Title: Signaling Pathways in
Central Nervous System Regeneration
Project Supervisor: JH Pate Skene, PhD
January 1993 – January 1995

Honors, Awards, Certifications and Memberships

American Board of Neurological Surgeons Maintenance of Certification examination 2010
American Association of Neurological Surgeons Medical Student Summer Research Fellowship for Krista Stewart 2010

American Association of Neurological Surgeons Neurosurgery Research and Education Foundation Fellowship (NREF) Award for Nirav Patel

2010
UW Hilldale Award for Tyler Wanke 2010
Children Matter Award, American Family Children’s Hospital 2010
CNS/Codman Fellowship Award for Nirav Patel 2009
Pediatric Neurosurgery Traveling Fellowship awarded to Elias Rizk for a clinical rotation (mentor) 2008

American Academy of Neurological Surgeons Resident Research Award for
Elias Rizk

2008
Citation for Medical Student Teaching, Department  of Neurological Surgery, UW 2008
  UW Hilldale Award for Krista Stewart 2008
  Pennsylvania Neurosurgical Society Resident Clinical Research Award for Elias Rizk 2007
  Citation for Medical Student Teaching, Department  of Neurological Surgery, UW 2007
Best Faculty Teaching Award, Department  of Neurological Surgery, UW 2006
Kenneth Schulman Award for Elias Rizk (best resident presentation at the AANS/CNS Section on Pediatric Neurosurgery) 2006
FASEB. Abstract chosen for oral presentation and $500 award. 2006
Pennsylvania Neurosurgical Society Resident Basic Research Award for Elias Rizk 2006

Kenneth Shulman Award for Joshua Medow

2004
Howard Hughes Medical Investigator, Pilot Project 2003 — 2005
Burroughs Wellcome Fund (BWF) Clinical Scientist
Awards in Translational Research (Winner of Univ
of Wisconsin internal competition)
2004
Think First Injury Prevention Program,
Lebanon Chapter Sponsor
2004 — present
Think First Injury Prevention Program,
Madison Chapter Sponsor
2003 — present
Hydrocephalus Association Award given to
Joshua Medow for best research paper
2003

Kenneth Shulman Award for Joshua Medow

2003
Shapiro Summer Research Award given to Jason Sansone 2003
American Society of Pediatric Neurosurgeons 2003
Fellow of the American Academy of Pediatrics 2002
Fellow of the American College of Surgeons 2002
American College of Surgeons Faculty Research Fellow 2000 — 2002
University Book Store Academic Excellence Award for
Aaron Nelson’s undergraduate thesis/laboratory work
2002
Honorable Mention (Engineering Expo):
Electrosurgical drill for endoscopic craniosynostosis
2001
Congress of Neurological Surgeons member
American Association of Neurological Surgeons member
AANS/CNS Section of Pediatric Neurosurgery member
Mayfield award of the AANS/CNS Spine section awarded to
Ketan Bulsara for a collaborative basic research project
2000
American Board of Neurological Surgery 2001
American Board of Pediatric Neurosurgery 2001
Alpha Omega Alpha Medical Honor Society 1995
National Board of Medical Examiners 1990
Special Olympics of Philadelphia:
Chairman, Ceremonies and Scheduling Committee
1988
Foundation for the Encouragement of Education in
Lebanon (FEEL), non profit organization.
Founding member and co-chairman of the Boston chapter
1987 — 1989
Phi Kappa Phi Honor Society 1985
 
Committee Memberships
UW Pediatric ICU staff recruitment Committee 1999
UW WISCR-IT (Computerized Records) Development Committee 1999 — 2000
UW Medical Board Nominating Committee 2000
Pediatric Plastic Surgeon Recruitment Committee 2000
Department of Orthopedics and Rehabilitation
Chairman Search Committee
2001
UW Pediatric Trauma Management Committee 2001 — present
Web GX Evaluation Committee 2002
UW Hospital Medical Board 2002 — 2004
World Association of Lebanese Neurosurgeons,
North American Representative
2002 — present
World Association of Lebanese Neurosurgeons,
Chairman, Education Committee
2004 — present
World Association of Lebanese Neurosurgeons Meeting,
Member, Scientific Program Committee
2004
American Family Children’s Hospital Clinics Committee 2003 — present
American Family Children’s Hospital Inpatient Units Committee 2003 — present
American Family Children’s Hospital Surgical Services Committee 2003 — present
American Family Children’s Hospital Diagnostic Pavilion Committee 2003 — present
Breakfast Seminar Panelist, AANS 2004
Search and Screen Committee for Chairman of Pediatrics 2004
Search and Screen Committee for Ophthalmology Staff Position 2004
American Syringomyelia Alliance Project,
Research Committee Member
2004 — present
UWMF Finance Committee 2005 — present
Think First National Injury Prevention Program.
Member of Efficacy Subcommittee
2005 — present
American Society of Pediatric Neurosurgeons (ASPN):
Chairman of Credentialing Committee
2006 — present

Regional, National, and International Courses

Issues in complex pediatric spine. The tethered spinal cord.
Luncheon seminar.
Congress of Neurological Surgeons (Invited Faculty).
1997
Neuroscope’99
Medtronic PS Medical Neuroendoscopy Workshop
New Orleans (Invited Faculty)
1999
First Annual Spine Symposium
American University of Beirut (Invited Faculty)
1999
Surgery of Brain Tumors in Children
Middle East Medical Assembly
Beirut (Invited Faculty)
2001
Intracranial Endoscopy
Congress of Neurological Surgeons (Invited Faculty)
2002
Hydrodynamics Conference
Pittsburgh, September (Invited Faculty)
2002
Head Injury Breakfast Seminar
American Association of Neurological Surgeons (Invited Faculty)
2003
Session Moderator (Hydrocephalus).
AANS/CNS Section on Pediatric Neurological Surgery
2003
UW Neuroscience Course. Faculty.
Topic: Hydrocephalus and ICP
2003 — Current
Chiari I Breakfast Seminal.
American Association of Neurological Surgeons (Invited Faculty)
2004
UW Neuroscience Course. Faculty.
Topic: Neurological Localization
2005 — Current
NIH Hydrocephalus Consensus
Conference (Session Moderator). Bethesda.
2005

Regional Conferences Organized

Severe Head Injury Management in Children
PICU/Neurosurgery Conference: Part I
The management of ICP
Organized by B. Iskandar and W. Perloff
November 1997
Severe Head Injury Management in Children
PICU/Neurosurgery Conference: Part II
Non–ICP–related issues in pediatric head injury
Organized by B. Iskandar
March 1998
Current Treatments and Innovations in Spina Bifida
Regional conference for patients with Spina Bifida and their families
Organized by B. Iskandar and B. Ohm
September 1998
Caring for Children with Brain Tumors
Regional conference co-director.
September 2000
Caring for Children with Brain Tumors
Regional conference co-director.
September 2005
American Syringomyelia and Chiari Alliance Project (ASAP) Annual Meeting, Local Host.  July 2009

Faculty Presentations

Issues in complex pediatric spine. The tethered spinal cord.
Luncheon seminar. Congress of Neurological Surgeons
October 1997
Hydrocephalus today
Pediatrics Grand Rounds
University of Wisconsin
August 1997
Head Injury
PICU nurses
September 1997
Spina bifida occulta
Perinatal Conference
Meriter Hospital / Park
September 1997
Management of pediatric head and spine injury
“Update in Pediatrics” annual conference
Wausau, WI
October 1997
Occult Spinal Dysraphism and the Tethered Spinal Cord
Family practice conference
Beaver Dam, WI
October 1997
Management of severe head injury:
Conclusions and future directions
Neurosurgery / PICU Head Injury Conference
University of Wisconsin
November 1997
Shunts
OR nurses
November 1997
Current trends in pediatric brain tumor management
Neurosurgery Grand Rounds
Teleconference with the Gunderson Clinic in LaCrosse, WI
November 1997
The Chiari Zero malformation
Pediatric Section of the AANS
December 1997
Split Cord Malformations in Myelomeningocele Patients
Pediatric Section of the AANS
December 1997
Central nervous system regeneration
Neurosurgery research conference
 
Current Management of Hydrocephalus
Pediatric conference
Dubuque, IA
January 1998
What’s special about the critical care of the head–injured child
Pediatric Head Injury Management Conference: Part II
University of Wisconsin Hospital
February 1998
The clinical and molecular characteristics of pediatric brain tumors
UW CME series
Rockford, IL
March 1998
The Neurological Assessment
Pediatric Basic Critical Care Course
University of Wisconsin Children’s Hospital
March 1998
Neurological assessment of the pediatric patient
Basic Critical Care Course
University of Wisconsin Children’s Hospital
March 1998
Shunts and shunt problems
Weekly pediatric resident conference
University of Wisconsin
April 1998
Surgery of the brachial plexus, with emphasis on obstetric palsies
Neurology Grand Rounds
University of Wisconsin
May 1998
The Chiari Malformations
“Progress in Pediatrics” annual conference
Madison, WI
May 1998
Pediatric Head Trauma Management
Dubuque, IA
June 1998
Hydrocephalus
Department of Rehabilitation conference
June 1998
Craniosynostosis
Pediatric Grand Rounds
University of Wisconsin
July 1998
Obstetric Plexus palsies
Pediatric department
Green Bay, WI
July 1998
Craniosynostosis
Neurosurgery / Neurology Grand Rounds
American University of Beirut
August 1998
Craniosynostosis
Updates in Pediatrics
Appleton, WI
October 1998
Shunts and Intracranial Pressure problems
Medical student pilot neuroscience course
October 1998
Shunts and Intracranial Pressure problems
Medical student pilot neuroscience course
December 1998
Hydrocephalus today
CME Wisconsin Radio Teleconference
November 1998
The current management of pediatric brain tumors
Neurology and Neurosurgery Grand Rounds
American University of Beirut
December 1998
Spina Bifida Occulta
Neurology / Neurosurgery Grand Rounds
American University of Beirut
December 1998
Current Trends in Myelomeningocele Treatment
Neonatology Grand rounds. Meriter Hospital.
January 1999
Spina Bifida Management. Urology Grand Rounds. UW. February 1999
Chiari Malformations and the Tethered Spinal Cord.
UW OR nursing conference.
May 1999
Management of Shunts and Shunt Infections.
Pediatric Residents Conference, UW
May 1999
Current Trends in the Management of Pediatric Head Injury. 
Pediatric Trauma/Management Conference. 
Kids First with Dr. C. Everett Koop. Greenbay.
May 1999
Ventricle size and CT scan reports. 
WALN Second Homecoming Meeting. Beirut
June 1999
Shunt Deaths in the 1990s.
WALN Second Homecoming Meeting. Beirut
June 1999
Upper Cervical Spine Fractures.
First Annual Spine Symposium. AUB.
June 1999
Pediatric Spine Trauma.
First Annual Spine Symposium. AUB.
June 1999
New Trends in Pediatric Neurosurgery.
Anesthesia Grand Rounds.
June 1999
Craniosynostosis.
WI State Society of Neurosurgery.
June 1999
Management of Brachial Plexus Lesions.
Neurosurgery residents conference.
July 1999
CNS Regeneration: Genetics vs. Environment.
Neurosurgery Grand Rounds/Research Conference.
August 1999
Pediatric Head Injury.
Fond-du-Lac Pediatrics Conference.
September 1999
Spina Bifida: Nature vs. Nurture. 
UW Pediatric Grand Rounds.
August 1999
Obstetric Plexus Palsies.
Perinatology/Neonataology Conference.
January 2000
Management of the Shunted Patient.
Pediatric Residents Conference.
February 2000
PDS Course. January 24 — 31, 2000
Spina Bifida in Modern Times: Nature vs. Nurture. 
Educational Teleconference Network.
March 2000
Caring for Children with Spina Bifida.
Surgical Care of Infants and Children: an update. 
Monona Terrace, Madison, WI.
March 2000
Pediatric Head and Spine Trauma.
Pediatric Critical Care course, UW Madison.
May 2000
The Role of Surgery in Pediatric Brain Tumor Management.
Caring for Children with Brain Tumors conference.
September 2000
Closing Large Myelomeningoceles.
Congress of Neurological Surgeons Luncheon Seminar.
Faculty Speaker.
September 2000
Modern Epilepsy Surgery.
Pediatric Grand Rounds.
August 2000
Managing Neonates with Spina Bifida. 
Meriter Neonatology Conference.
September 2000
New Observations in Syringomyelia. 
Pan Arab Neurosurgical Society.
October 2000
Syringomyelia: I don’t get it.
Neurosurgery Grand Rounds.
November 2000
Epilepsy. Fond-Du-Lac Community meeting. November 2000
Spinal cord pulsations as a determinant of
pathological pressure within a syrinx.
AANS/CNS Pediatric Section.
December 2000
Brain embryology, Part I.
UW Neurosurgery Residents’ Conference.
January 2001
Neonatal hemorrhage.
Meriter Neonatology/Perinatology Conference.
January 2001
Hydrocephalus and shunts.
UW Department of Rehabilitation Resident Conference.
February 15, 2001
Neuroanatomy for medical students.
UW medical student talk.
March 2001
Brain embryology, Part II.
UW Neurosurgery Residents’ Conference.
March 2001
Pediatric neurosurgical critical care.
UW pediatric critical care course.
April 2001
Folic acid supplementation enhances CNS regeneration.
AANS. Toronto.
April 2001
Intracranial Pressure and Hydrocephalus.
UW Neuroscience Pilot Course.
May 2001
Pediatric Brain Tumors.
Middle East Medical Assembly. Beirut.
May 2001
The Role of Folic Acid in CNS Regeneration.
UW Neurosurgery Grand Rounds
May 2001
YEPSA Medical Student Examinations. June 2001
The Management of Encephaloceles and Chiari Malformations,
UW Neonatology/Perinatology conference.
June 2001
Surgery of the Brachial Plexus.
UW Plastic Surgery Grand Rounds.
June 2001
Cranial Shape Abnormalities.
Peidatric Grand Rounds. Dubuque.
Sept 2001
Idiopathic Sryingomyelia.
Congress of Neurological Surgeons. San Diego.
October 2001
Hydrocephalus.
UW Pediatric Residents Conference.
December 2001
Folic Acid in CNS Regeneration.
AANS/CNS Joint Section of Pediatric Neurosurgery.
December 2001
Cranial Shape Problems and Positional Molding: WAPNAP. October 2001
Hydrocephalus.
Pediatric Residents Conference.
December 2001
Brachial Plexus Surgery.
Mercy Medical Grand Rounds.
Oshkosh WI.
February 2002
Research in Clinical Practice.
UW Neuroscience Society. UW.
February 2002
Cranial Shape Anomalies.
Surgical Care of Infants and Children: 2002.
Fluno Center, Madison WI.
February 2002
Embryology of the Brain and Brain Malformations.
UW Neurosurgery Resident Conference.
February 2002
Embryology of the Brain and Brain Malformations.
UW Neurosurgery Resident Conference.
April 2002
Embryology of the Spine and Spinal Malformations.
UW Neurosurgery Residents Conference.
June 2002
Hydrocephalus. UW Medical Student Neuroscience Course. August 2002.
Endoscopic Resection of Colloid Cysts.
Congress of Neurological Surgeons.
Philadelphia PA.
September 2002
CSF Flow Studies in Patients with Chiari I Malformation.
Hydrodynamics Conference.
Pittspburgh.
September 2002
Neurological Problems in Critical Care Nursing.
Critical Care Nursing (Regional) Conference.
Madison WI.
September 2002
Folate antagonists in CNS Regeneration.
American College of Surgeons.
San Francisco CA.
October 2002
Folic acid enhances repair mechanisms in the CNS.
American Academy of Neurological Surgeons.
Phoenix AZ.
October 2002
Hydrocephalus.
Pediatric Residents Conference.
November 2002
Hydrocephalus. UW Medical Student Neuroscience Course. November 2002
Brain Embryology.
Neurosurgery Residents Conference.
January 2003
Hydrocephalus. UW Medical Student Neuroscience Course. February 2003
Pediatric Head Trauma Management. UW Trauma Conference. March 2003
Care of the Pediatric Neurosurgical Patient.
Pediatric Intensive Care Conference. UW.
April 2003
Hydrocephalus. UW Medical Student Neuroscience Course. April 2003
Brainstem Anatomy.
UW Medical Student Neuroanatomy Course.
April 2003
Flat Heads: When to Worry, What to Do.
AAP Regional conference.
April 2003
Spine Embryology.
Neurosurgery Residents Conference.
May 2003
Hydrocephalus. UW Medical Student Neuroscience Course. May 2003
Surgery for Brachial Plexus Injuries.
UW Plastic Surgery Grand Rounds.
June 2003
Hydrocephalus. UW Medical Student Neuroscience Course. July 2003 — June 2004
CSF flow dynamics in the foramen magnum of
children with Chiari I malformations ASAP.
New York City.
July 2003
Folic Acid in CNS Repair. SCIRP meeting.
UW School of Veterinary Medicine.
August 2003.
Hydrocephalus. Pediatric Resident Conference. October 2003
Diagnostic Pitfalls in Hydrocephalus.
Weekend Course on Hydrocephalus (Invited Faculty).
Congress of Neurological Surgeons, Denver.
October 2003
Lumps, Bumps, and Holes: Windows to the Spine.
Pediatric Grand Rounds.
November 2003
Session Moderator (Hydrocephalus).
AANS/CNS section on pediatric neurological surgery.
December 2003
The Folate Pathway in CNS Repair.
SCIRP meeting. UW School of Veterinary Medicine.
February 2004
Chiari Flow Studies.
American Society of Pediatric Neurosurgeons.
Costa Rica.
February 2004
Cranial Shape Anomalies.
UW Pediatric Residents Conference.
March 2004
Pediatric Head Injury.
Pediatric Critical Care Conference.
March 2004
Congenital Hydrocephalus.
Neonatology/Perinatology Conference.
Meriter Hospital.
March 2004
Surgery for Hydrocephalus.
UW Anesthesia Grand Rounds.
March 2004
Spina Bifida.
Spina Bifida Family Network.
May 2004
Hydrocephalus. UW OR Nurses. May 2004
Chiari I Malformation.
AANS Breakfast Seminar.
May 2004
Brachial Plexus Surgery.
Plastic Surgery Grand Rounds.
June 2004
Hydrocephalus: To shunt or not to shunt. WALN.
Beirut.
July 2004
Folic acid in CNS Repair. Neuroscience. July 2004
Neuroanatomy of the Brainstem. Pediatric Resident Conference. August 2004
Spina Bifida Occulta. Dean Pediatrics Conference. September 2004
Shunt Management. Learning Science Center talk series. October 2004
Spinal Anomalies. Seminars in Pediatrics. Madison. October 2004
Hydrocephalus. UW Neurosurgery Grand Rounds. January 2005
Neuroembryology.
UW Pediatric Resident Conference.
July 2005
The Sodium Potassium ATPase Pump is essential in CNS regeneration
(AANS/CNS Section on Pediatric Neurosurgery, Orlando).
2005
The role of DNA methylation in CNS regeneration
(Neural Tube Defects meeting).
2005
The role of DNA methylation in CNS regeneration
(American Academy of Neurological Surgeons, San Francisco).
2005
Session Moderator (invited).
NIH Hydrocephalus consensus conference.
Fall 2005
Surgery for Pediatric Brain Tumors.
Caring for Children with Brain Tumors regional conference.
Sept. 2005
Spina Bifida Occulta.
UW regional pediatric conference.
St. Elizabeth Hospital, Appleton, WI.
October 2005
Shunt Issues with Pseudotumor cerebri. Department of Ophthalmology Grand Rounds. January 2006.
Pediatric Neurosurgery in Uganda.  UW Neurosurgery Grand Rounds. May 2006.
UW Pediatric Residents Conference.  May 2006.
The Sodium Potassium ATPase Pump in CNS Regeneration. UW Neurosurgery Research Seminar. September 2006.
CNS Regeneration: An Update. Dr. Vemuganti’s Neuroscience Course. UW Madison. December 2006.
More on the Folate Pathway and CNS Repair.  UW Neurosurgery Grand Rounds. September 2007.
The Folate Pathway and CNS Repair.  UW Neurology Grand Rounds. . September 2007
Review in CNS Regeneration & Article Review. Neuroscience NTP 675 UW Course. October 2007.
The Role of the Folate Pathway in CNS Regeneration and Repair. NTD Research Meeting.. Monterey. September 2007. Neurosurgery Research Day. October 2007.
Cervical Spinal Cord Injury in Neonates. UW Perinatology Conference. October 2007
Hydrocephalus: Care Perspectives. Appleton Perinatology Conference. November 2007
Lumps Bumps and Holes: Window to the Spine.  Appleton Perinatology Conference. November 2007
Pediatric Neurosurgery: The Specialty.  AFCH. November 2007
Brachial Plexus Surgery. UW Plastic Surgery Grand Rounds. August 2008
Going Beyond Survival: How we Improve Quality of Life in Children and Adults with Spina Bifida.  UW Pediatric Grand Rounds. August 2009
Brachial Plexus Management. UW Plastic Surgery Grand Rounds.  August 2009
Neuroscience NTP 675 Course: Speaker, Review in CNS Regeneration & Article Review. September 2009
Undergraduate NTP Research Seminar: Speaker, CNS regeneration and the folate pathway. March 2010
Brachial Plexus Surgery.  Orthopedics Grand Rounds.  April 2010
Pediatric Neurooncology: An update.  Neurology Resident Conference.  May 2010

Journal Reviews and Editorial Boards

Pediatric Neurosurgery
Past Journal Reviewer
Practical Reviews in Neurosurgery
Previous Editorial Board Member and the Pediatric Neurosurgery Reviewer
J Neuropath Exp Neurol
Ad Hoc Reviewer
Prince Salman Center for Disability Research
Ad Hoc Reviewer
Journal of Genetic Counseling
Ad Hoc Reviewer
Child’s Nervous System
Discussant
Annals of Neurology
Ad Hoc Reviewer
AANS/CNS Pediatric Section
Abstract Reviewer
2004-5
CNS Pediatric Neurosurgery
Abstract Reviewer
2005
Clinical Anatomy
Ad Hoc Reviewer
Archives of PM&R
Ad Hoc Reviewer
The Scientific World
Ad Hoc Reviewer
Neurpediatrics
Ad Hoc Reviewer
Journal of Nutritional Biology
Ad Hoc Reviewer
Neurosurgery
Ad Hoc Reviewer
Pediatrics
Ad Hoc Reviewer
Pan Arab Journal of Neurosurgery
Editorial Board member

Congenital Section: ISPN Web Book on Pediatric Neurosurgery
Editor

Pediatric Neurosurgery Boards Questions
Contributor
2009-2010
Chiari and Syringomyelia Foundation Website educational section
Editor
Grant Reviewer: NICHD / NIH
2010

Clinical Trials

Endoscopic Shunt Insertion Trial
Local Primary Investigator
Multi-center trial
Based in Vancouver, Canada
Genetic Study of Neural Tube Defects
Local Primary Investigator
Multi-Center trial
Based at Duke University Medical Center, Durham, NC
Shunt Infection Trial
Local Primary Investigator
Multi-center trial
Based in Utah
Folic acid in Pediatric Head Injury
Primary Investigator
Randomized controlled trial
CSF Flow Studies in Chiari I malformation
Local Primary Investigator

Research Support

Howard Hughes Medical Investigator Pilot Project
Title: Folate antagonists in the injured adult CNS
The goal of this study is to identify the effect of select
folate antagonists on CNS regeneration and recovery after injury.
This study is providing the preliminary data needed for the
in-depth study of the mechanism by which the folate pathway
participates in CNS repair, as proposed in this application.
Role: PI
Effort: 25%
2003 — 2005
American Syringomyelia Alliance Project $210,000
Title: Multi-Center Chiari Clinical Trial
Role: PI
Current
NIH 1R01HD047516-01 $878,672
Title: Folic acid enhances repair in the adult CNS.
The objective of this study is to identify the mechanism of
action of the folate and methionine-methylation pathway in
CNS regeneration and recovery from injury. Role: PI Effort: 25%
2006 — 2011
NIH 3R01HD047516-04S1 ARRA Supplement
Title:  Folic acid enhances repair in the adult CNS.
Role:   PI
Effort: 20% in conjunction with 1R01HD047516-01
9/2009-9/2011
1R15NS071455-01 NIH R15 $486,117
Title: Clinical Utility of MR based Hydrodynamic Parameters in Chiari Malformation.
Role:  Collaborator
5/2010-4/2012
Folic Acid Increases Spinal Cord Regeneration Across Multiple Generations-NREF Fellowship (Mentor for Dr. Nirav Patel) 7/2010-6/2011

Patents Approved or Pending

P01334US
Electrosurgical drill for endoscopic craniosynostosis
Activation of axon repair by defined gene combinations CAP23/GAP43

5-methyltetrahydrofolic acid as therapy for tissue injury.  Patent 61/075, 650 filed June 25, 2008.

Nitrous Oxide Epigenetic Switch (patent pending), submitted April 2010.

Trainees Mentored

Agahan Unlu, MD
Postdoctorate Trainee
1999
Christine Schwab
Medical Scholars Program
1998
Gregory Griepentrog
Medical Scholars Program
2000
Michael Hendrickson
Medical Scholars Program
2001
Peng Gao, MD
Research Scientist
2001 — 2002
Aaron Nelson
UW Undergraduate Thesis
2001 — 2002
Julie Pawasarat
UW Directed Study of Research
2001 — 2002
Rebecca Allen
NASA/Sharp Program
1999
Jessica Renee Mendellin
NASA/Sharp Program
2001
Chenara Johnson
NASA/Sharp Program
2000
Michael Murphy
Medical Scholars Program
2002
Aaron Struck
Medical Scholars Program
2003
Frances Delgado
UW Undergraduate Thesis
2002 — 2003
Brenton Meier
UW Undergraduate Research
2002 — 2003
Elias Rizk
Research Scientist
2004
Abigail Poyer
NASA/Sharp Program
2004
Kate Holoyda
Medical Scholars Program
2004
Abigail Rao
Medical Scholars Program
2005
Aaron Struck
Shapiro award
Summer 2005
Kathleen Simon
UW Independent Study Course
2005
James Davies
UW Independent Study Course
2005

Prethy Rao: UW Independent Study Course

2006

Andrew Jacus: UW Independent Study Course
2006
Park Byoung-Gyu: UW Independent Study Course
2006
Sadhana Murali: UW Directed study course
2007
Sarah Bassiouni: UW Independent Study Course
2008
Roman Ayele Aydiko: UW Independent Study Course
2008
Mina Zamanian: UW Independent Study Course
2008
Logan Gorges: UW Independent Study Course
2008-9
Krista Stewart: UW Independent Study Course
2007-9
Sharad Rajpal, UW Neurosurgery Resident
2007-8
Nirav Patel, UW Neurosurgery Resident
2008-present
Andrew Bauer, UW Neurosurgery Resident
2008-present
Solomon Ondoma: Postdoctoral Fellow
2008-present
Sivan Meethal: Scientist
2010-present
Krista Stewart: AANS Medical Student Summer Research Award
2010-present
Tyler Wanke: Undergraduate Research
2009-10
Anaita Chindhy: Undergraduate Research
2009-10
Pascale Styles: Undergraduate Research
2009-10
Wren Keturi: Undergraduate Research
2009-10
Kara Weber: Undergraduate Research
2009-10
Rebecca Furdek: Undergraduate Research
2009-10
Michael Mendoza: Undergraduate Research
2009-10
Thomas Kuehn: Undergraduate Research
2009-10
Heidi Johng: Undergraduate Research 2009-10

Patient Education Publications

Ohm B, Iskandar BJ. Craniosynostosis. UW Health Facts..
Ohm B, Iskandar BJ. Hydrocephalus. UW Health Facts.
Ohm B, Iskandar BJ. Selective Dorsal Rhizotomy. UW Health Facts.
Ohm B, Iskandar BJ. Intrathecal Baclofen Pumps for Severe Spasticity. UW Health Facts.
Ohm B, Iskandar BJ. Brachial Plexus Injury in Infants. UW Health Facts.
Ohm B, Iskandar BJ. Shunt Series. UW Health Facts.
Ohm B, Iskandar BJ. Tethered Cord UW Health Facts.
Ohm B, Iskandar BJ. Intracranial Pressure Monitoring. UW Health Facts.
Ohm B, Iskandar BJ. Epilepsy Surgery. UW Health Facts.
Ohm B, Iskandar BJ. Shunt Series. UW Health Facts.
Ohm B, Iskandar BJ. Chiari I Malfromation. UW Health Facts.
Iskandar BJ, Ramirez L. Cranial Shape Anomalies. UW Pediatric Neurosurgery Educational Panel.
Iskandar BJ, Ramirez L. Neurologic Problems in Spina Bifida. UW Pediatric Neurosurgery Educational Panel.
Iskandar BJ, Ramirez L. Hydrocephalus. UW Pediatric Neurosurgery Educational Panel.
Iskandar BJ. Chiari I.  Educational Section.  www.CSFinfo.org Web Page. 2010.
Iskandar BJ. Syringomyelia. Educational Section.  www.CSFinfo.org Web Page. 2010.
Iskandar BJ. Chiari II. Educational Section.  www.CSFinfo.org Web Page. 2010.

Publications

Iskandar BJ, Oakes WJ, McLaughlin C, Osumi A, and Tien RD: Terminal Syringohydromyelia and Occult Spinal Dysraphism. J Neurosurg 81(4):513-519, 1994 (with cover illustration).
 Iskandar BJ, Kapp JP: Nonseptic venous occlusive disease. In Wilkins RH, Rengachary SS (eds.): Neurosurgery. Second edition, McGraw Hill, New York, NY.
Iskandar BJ, Graham DG: Intracranial lipomas. In Wilkins RH, Rengachary SS (eds.): Neurosurgery. Second edition, McGraw Hill, New York, NY.
Iskandar BJ, Nashold BS Jr: History of functional neurosurgery. Neurosurgery Clinics of North America 6(1):1-25, 1995.
Iskandar BJ, Nashold BS Jr: Spinal and Trigeminal DREZ Lesions. In Gildenberg PL, Tasker RR (eds.): Textbook of Stereotactic and Functional Neurosurgery. McGraw Hill, New York, NY.
Ovelmen-Levitt J, Gorecki J, Nguyen B, Iskandar BJ, Nashold BS Jr: Spontaneous and Evoked Dysesthesias Observed in the Rat after Spinal Cordotomies. Journal of Stereotactic and Functional Neurosurgery 65 (1-4):157-60, 1995.
Iskandar BJ, Oakes WJ: Occult Spinal Dysraphism.  In Albright AL, Pollack IF, Adelson PD (eds.): Principles and Practice of Pediatric Neurosurgery. Thieme Thieme Medical Publishers, New York, NY (1999).
Iskandar BJ, Oakes WJ: The Chiari Malformations. In Albright AL, Pollack IF, Adelson PD (eds.): Principles and Practice of Pediatric Neurosurgery. Thieme Medical Publishers, New York, NY (1999).
Iskandar BJ, McLaughlin C, Mapstone TB, Grabb PA, Oakes WJ: Pitfalls in the diagnosis of ventricular shunt dysfunction: Radiology reports and ventricular size. Pediatrics 101(6): 1031-1036, 1998.
Iskandar, BJ, Hedlund G, Grabb PA, Oakes WJ: The resolution of syringomyelia after posterior fossa decompression. J Neurosurg 89(2):212-216, 1998.
Iskandar BJ, Fulmer B, Hadley M, Oakes WJ: Congenital tethered spinal cord in adults. J Neurosurg 88:958-961, 1998.
Iskandar BJ, Tubbs S, Mapstone T, Grabb PA, Bartolucci AA, Oakes WJ: Shunt Deaths in the 1990s. Pediatric Neurosurgery 28:173-176, 1998
Iskandar BJ, Oakes WJ: Anomalies of the Spine and Spinal Cord.  In McLone D (ed.): Pediatric Neurosurgery, W.B.Saunders, Philadelphia, PA.
Iskandar BJ: Current trends in the management of hydrocephalus, in Picture of Health television series,1998.
Rauzzino MJ, Iskandar B, Oakes WJ: Occult Spinal Dysraphism. Contemporary Neurosurgery 20(22):1-6, 1998.
Iskandar BJ, McLaughlin C, Oakes WJ: Split Cord Malformations in Myelomeningocele Patients. British Journal of Neurosurgery 14(3):200-3, 2000
Binder DK, Iskandar BJ: Modern neurosurgery for psychiatric disorders. Neurosurgery 47(1): 9-23, 2000.
Sheth R, Iskandar BJ: Craniosynostosis.  eMedicine Neurology  http://www.emedicine.com/neuro/index.shtml, (chapter for web based book), 2000.
Nguyen P, Iskandar BJ: Congenital intracranial cysts.  YourDoctor.com (chapter for web based book, in press)
Iskandar BJ, Grabb P, Oakes WJ: Chiari Zero: The resolution of syringomyelia after posterior fossa decompression. Neurosurgical Focus 8(3): article 5, 2000.
Bomze HM, Bulsara KR, Iskandar BJ, Caroni P, Skene JHP: Activation of spinal axon regeneration by replacing two growth cone proteins in adult neurons. Nature Neuroscience 4(1):38-43, 2001.
Iskandar BJ, Ramirez L: An illustrated guide to epilepsy surgery.  Seminars in Pediatric Neurology 7(3):224-240, 2000.
Melvin EC, George TM, Worley G, Franklin A, Mackey J, Viles K, Shah N, Drake CR, Enterline DS, McLone D, Nye J, Oakes WJ, McLaughlin C, Walker ML, Peterson P, Brei T, Buran C, Aben J, Ohm B, Iskandar BJ, Qumsiyeh M, Vance J, Perlcak-Vance MA, Speer MC and the NTD Collaborative Group: Genetic Studies in Neural Tube Defects. Pediatr Neurosurg 32:1-9, 2000.
Haughton VM, Turski PA, Iskandar BJ, Dempsey RD, Badie B, Chahal RS, and Meyerand ME: Clinical utility of fMRI in the preoperative evaluation of patients with cerebral lesions (submitted).
Bulsara KR, Iskandar BJ, Villavicencio AT, Skene JHP. A New Millenium for Spinal Cord Regeneration:  Growth Associated Genes.  Spine 27:1946-1949, 2002.
Iskandar BJ, Nelson A, Skene JHP, Gao P, Johnson C, Resnick DK & Hariharan N: Folic acid supplementation enhances repair mechanism in the adult CNS (submitted).
Unlu A, Hariharan N, Iskandar BJ: Spinal cord regeneration induced by a voltage-gated calcium channel agonist. Neurological Research 24:639-642, 2002.
Haughton V, Korosek F, Medow J, Dolar M, Iskandar BJ: Peak systolic and diastolic CSF velocity in the foramen magnum in adult Chiari I patients and normal subjects AJNR 24:168-176, 2003.
Swartz KR, Resnick DK, Iskandar BJ, Wargowski D, Brockmeyer D, Opitz JM:  Craniocervical Anomalies in Dubowitz Syndrome. Three Cases and a Literature Review. Pediatric Neurosurgery 38:238-243, 2003.
Maganti R, Rutecki P, Bell B, Woodard A, Jones J, Ramirez L, Iskandar B: Epilepsy Surgery Outcome Among United States Veterans Epilepsy and Behavior 4(6):723-8, 2003.
Dolar MTV, Haughton VM, Iskandar BJ, Quigley M. Effect of suboccipital craniectomy on CSF flow velocity in patients with Chiari I malformations AJNR 25:142-145, 2004.
Badie B, Prabakaran S, Salamat S, Vemuganti R, Dhodda V, Iskandar BJ, Schartner J.  GeneChip Analysis Reveals Variation in Gene Expression Among Low-Grade Oligodendrogliomas.
Iskandar BJ, Mount D: Flat Heads: When to Worry, What to Do. The WIsper November 2003.
Lapsiwala S, Iskandar BJ: Congenital tethered cord presenting in adulthood: A review Neurological Research 26:735-40, 2004 .
Iskandar BJ: Comments: Russell Silver Syndrome and Tethered Spinal Cord. Child’s Nervous System 20 (7): 480-82, 2004.
Tubbs RS, Wellons JC 3rd, Iskandar BJ, Oakes WJ. Isolated flat capillary midline lumbosacral hemangiomas as indicators of occult spinal dysraphism. Journal of Neurosurgery-Pediatrics. 100(2):86-9, 2004.
Tubbs RS, Oakes WJ, Iskandar BJ. Response: Isolated flat capillary midline lumbosacral hemangiomas as indicators of occult spinal dysraphism. Journal of Neurosurgery-Pediatrics. 100(2):81-2, 2004.
Iskandar BJ, Sansone JM, Medow J, & Rowley H: The Use of “Quick-Brain” MRI in the Evaluation of Shunted Hydrocephalus. J Neurosurg-Pediatrics 101:147-151,2004
Iskandar BJ, Quigley M, Haughton V: Effect of posterior fossa decompression on CSF flow pattern in the foramen magnum of children with Chiari I malformations. J Neurosurgery-Pediatrics 101:169-178,2004.
Iskandar BJ, Nelson A, Resnick DK, Skene JHP, Gao P, Johnson C, & Hariharan N: Folic acid supplementation enhances repair mechanism in the adult CNS. Annals of Neurology 56:221-227,2004.
Quigley MF, Iskandar BJ, Mistretta CA, Haughton VM. Spatial and Temporal Characterization of CSF flow in the foramen magnum in normal subjects and patients with Chiari I malformations. Radiology 232:229-236,2004..
Medow J, Sansone J, Iskandar BJ: Syringomyelia and Hydromyelia. In Albright AL, Pollack IF, Adelson PD (eds.): Principles and Practice of Pediatric Neurosurgery. 2nd ed. Thieme Medical Publishers, New York, NY (in press).
Tubbs S, Iskandar BJ, Bartolucci AA, Oakes WJ: A Critical Analysis of the Chiari 1.5 Malformation. J Neurosurg-Pediatrics 101:179-183,2004.
Rajpal S, Iskandar BJ: Posterior Fossa Tumors in Children. Atlas of Neurosurgery.  AANS (in press).
Turk A, Iskandar BJ, Haughton V, Consigny D. Recording CSF pressure with a transducer-tipped wire in an animal model of Chiari I. AJNR Am J Neuroradiol 27(2):354-5, 2006.
Sansone J, Mann D, Noonan K, McLeish D, Iskandar BJ: Rapid Progression of Scoliosis Following Insertion of Intrathecal Baclofen Pump Journal of Pediatric Orthopedics 26(1):125-128, 2006.
Iskandar BJ, Haughton V. Peak CSF Velocities in the Foramen Magnum Vary with Age. J Neurosurg (6 Suppl Pediatrics) 103:508–511, 2005
Sansone J, Iskandar BJ. Endoscopic Cerebral Aqueductoplasty: A Trans-Fourth Ventricle Approach. J Neurosurg: Peds. 103:388-92, 2005 (Cover Picture).
Iskandar BJ, Sansone J. Editorial Response. Endoscopic Cerebral Aqueductoplasty: A Trans-Fourth Ventricle Approach. J Neurosurg: Peds 103, 2005.
Iskandar BJ, Quigley M, Haughton V: Effect of posterior fossa decompression on CSF flow pattern in the foramen magnum of children with Chiari I malformations. J Neurosurgery-Pediatrics 101:169-178,2004.
Iskandar BJ, Nelson A, Resnick DK, Skene JHP, Gao P, Johnson C, & Hariharan N: Folic acid supplementation enhances repair mechanism in the adult CNS. Annals of Neurology 56:221-227,2004.
Quigley MF, Iskandar BJ, Mistretta CA, Haughton VM. Spatial and Temporal Characterization of CSF flow in the foramen magnum in normal subjects and patients with Chiari I malformations. Radiology 232:229-236,2004..
Tubbs S, Iskandar BJ, Bartolucci AA, Oakes WJ: A Critical Analysis of the Chiari 1.5 Malformation. J Neurosurg-Pediatrics 101:179-183,2004.
Turk A, Iskandar BJ, Haughton V, Consigny D. Recording CSF pressure with a transducer-tipped wire in an animal model of Chiari I. AJNR Am J Neuroradiol 27(2):354-5, 2006.
Sansone J, Mann D, Noonan K, McLeish D, Iskandar BJ: Rapid Progression of Scoliosis Following Insertion of Intrathecal Baclofen Pump. Journal of Pediatric Orthopedics 26(1):125-128, 2006.
Iskandar BJ, Haughton V. Peak CSF Velocities in the Foramen Magnum Vary with Age. J Neurosurg (6 Suppl Pediatrics) 103:508–511, 2005
Sansone J, Iskandar BJ. Endoscopic Cerebral Aqueductoplasty: A Trans-Fourth Ventricle Approach. J Neurosurg: Peds. 103:388-92, 2005 (Cover Picture).
Iskandar BJ, Sansone J. Editorial Response. Endoscopic Cerebral Aqueductoplasty: A Trans-Fourth Ventricle Approach. J Neurosurg: Peds 103, 2005.
Moftakhar R, Salamat S, Sahin S, Iskandar BJ. Endoscopically-assisted resection of a choroid plexus vascular malformation traversing the cerebral aqueduct. Neurosurgery 59 (ONS Suppl 1):ONS-161, 2006.
Halanski MA, Iskandar BJ, Nemeth B, Nounan KJ. The Coconut Condyle: occipital condylar dysplasia causing torticollis and leading to C1 fracture. J Spinal Disord Tech 19(4):295-8, 2006.
Rusbridge C, Greitz D, Iskandar BJ. Syringomyelia: Current concepts in pathogenesis, diagnosis and treatment. J Vet Intern Med 20:469–479, 2006.
Struck AF, Murphy MJ, Iskandar BJ. Spontaneous development of a de novo suprasellar arachnoid cyst. Case Report. J Neurosurg:Pediatrics 104:426–428, 2006.
Turk Q, Iskandar B, Haughton V, Consigny D. Recording CSF Pressure with a Transducer-tipped Wire in an Animal Model of Chiari I. AJNR Am J Neuroradiol 27:354 –355, 2006.
Boyles AL, Enterline DS, Hammock PH, Siegel DG, Slifer SH, Mehltretter L,Gilbert JR, Hu-Lince D, Stephan D, Batzdorf U, Benzel E, Ellenbogen R, Green BA,Kula R, Menezes A, Mueller D, Oro JJ, Iskandar BJ, George TM, Milhorat TH, Speer MC. Phenotypic definition of Chiari type I malformation coupled with high-density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15. Am J Med Genet 140(24):2776-85 2006.
Tubbs RS, Shoja MM, Acakpo-Satchivi L, Wellons JC 3rd, Blount JP, Oakes WJ, Iskandar BJ. Exposure of the V1-V3 segments of the vertebral artery via the posterior cervical triangle: a cadaveric feasibility study. J Neurosurg Spine 5(4):320-3 2006.
Griepentrog GJ, Aagaard-Kienitz B, Kushner BJ, Iskandar BJ, Strother CM, Gamm DM. Dural Arteriovenous Fistula Presenting as Unilateral Upper Lid Sw elling and Ptosis in an Infant. Arch Ophthalmol 124(9):1359-61, 2006.
Rajpal S,Tubbs RS, George TM, Oakes JW, Hadley MN, Iskandar BJ. Congenital tethered cord in adults: Retrospective analysis of 61 cases. J Neurosurg Spine 6(3):210-5, 2007.
Sahin S, Shaaban AF, Iskandar BJ. Recurrent pneumoniae caused by transdiaphragmatic erosion of VP shunt into the lung. J Neurosurg. 2007 Aug;107(2):156-158.
Rajpal S, Salamat S, Tubbs RS, Oakes JW, Iskandar BJ. Tethering Tracts in Spina Bifida Occulta: Revisiting an Established Nomenclature.  J Neurosurg: Spine. 2007 Sep;7(3):315-22.
Hofkes S, Iskandar BJ, Turski PA, Gentry L, McCue J, Haughton VM. Differentiation of symptomatic Chiari I malformation from asymptomatic tonsilar ectopia by CSF flow imaging–an initial estimate of the accuracy of imaging. Radiology. 2007 Nov;245(2):532-40.
Acakpo-Satchivi L, Shannon CN, Tubbs RS, Wellons JC 3rd, Blount JP, Iskandar BJ, Oakes WJ. Death in shunted hydrocephalic children: a follow-up study. Childs Nerv Syst. 2008 Feb;24(2):197-201. Epub 2007 Jun 27.
Rocque B, Lapsiwala S, Iskandar BJ. Ventricular Shunt Tap as a Predictor of Proximal Shunt Malfunction in Children: a Prospective Study J Neurosurg Pediatrics. 2008 Jun;1(6):439-43.
The role of the Sodium Potassium ATPase Pump in CNS regeneration ( in preparation)
Location of injury along a CNS axon affects the extent of axonal regeneration (in preparation)
Iskandar BJ (Book Editor): Pediatric Neurosurgery Supplement for Pan-Arab Journal of Neurosurgery, 2008.
Rajpal S, Iskandar BJ. Non-Tumor Neurondoscopy. In Iskandar BJ (ed.) Pediatric Supplement to Pan Arab Journal of Neurosurgery, 2008.
Bauer A, Iskandar BJ.  The Chiari Malformations and Syringomyelia. In Neurosurgery-on-call, CNS 2008.
Kiehn MW, Derrick AJ, and Iskandar BJ. Two Unusual Anatomic Variations Create a Diagnostic Dilemma in Distal Ulnar Nerve Compression. Clinical Anatomy 21(6):592-7, 2008.
Deak KL, Siegel DG, George TM, Gregory S, Ashley-Koch A, Speer MC; NTD Collaborative Group. Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects. Birth Defects Res A Clin Mol Teratol 82(10):662-9, 2008
Martin BA, Royston TJ, Oshinski JN, Iskandar B, Loth F. Spinal Canal Pressure Measurements in an In Vitro Stenosis Model: Implications on Syringomyelia Theories. Journal of Biomechanical Engineering (accepted).
Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, Jarrard DF, Banerjee RV, Skene JH, Nelson A, Patel N, Gherasim C, Simon K, Cook TD, Hogan KJ. Folate Regulation of CNS Regeneration through DNA Methylation. The Journal of Clinical Investigation 120(5):1603-1616, May 2010.
Ansari S, Andrabi Y, El Khashab M, Bateni F, Dadmehr M, Iskandar BJ, Nejat F. Triple lumbar dermal sinuses: unusual presentation of a typically solitary midline lesion. Pediatr Neurosurg. 45(4):305-7, Aug 2009.

Published Abstracts

Iskandar B, Rossitch E Jr, Ovelmen-Levitt J, and Nashold BS Jr: The effects of prior local anesthesia on the expression of the deafferentation syndrome following C5-T2 ganglionectomies in the rat. Society for Neuroscience 18:385, 1992.
Iskandar BJ, Oakes WJ, McLaughlin C, Osumi A, and Tien RD: Terminal Syringohydromyelia. Section on Pediatric Neurological Surgery of the American Association of Neurological Surgeons, Vancouver, B.C., Canada, December 1992.
Harris T, Ovelmen-Levitt J, Iskandar BJ, Rossitch E Jr, Levitt M, Urban B, Nashold BS Jr: Does injury discharge initiate the deafferentation syndrome following C5-T2 ganglionectomies in the rat? Society for Neuroscience 19:519, 1993.
Ovelmen-Levitt J, Harris T, Iskandar B, Rossitch E Jr, Urban B, Nashold BS Jr: Effects of topical and systemic Bupivacaine on the development of the deafferentation syndrome in the rat. International Pain Meeting, Seventh World Congress on Pain (Paris). Pain (Suppl 6), 1993.
Ovelmen-Levitt J, Harris T, Nguyen B, Iskandar B, Gorecki J, Nashold BS Jr: Postcordotomy spontaneous dysesthesias in the rat. North Carolina Society for Neuroscience, 1994 (abstract #11).
Iskandar BJ, McLaughlin C, Mapstone TB, Grabb PA, Oakes WJ: Pitfalls in the diagnosis of ventricular shunt dysfunction: Radiology reports and ventricular size.  Presented at the Joint Section of Pediatric Neurosurgeons, Charleston, SC, 1996.
Iskandar BJ, Tubbs SA, Mapstone TB, Grabb PA, Oakes WJ: Shunt deaths in the 1990s.  Presented at the American Society of Pediatric Neurosurgeons, 1997.
Iskandar, BJ, Hedlund G, Grabb PA, Oakes WJ: The Chiari zero malformation . Presented at the Joint Section of Pediatric Neurosurgeons, New Orleans, 1997.
Iskandar BJ, Fulmer B, Hadley M, Oakes WJ: Congenital tethered spinal cord in adults.  Presented at the American Association of Neurological Surgeons, Denver, CO, 1997.
Iskandar BJ, McLaughlin C, Oakes WJ: Split Cord Malformations in Myelomeningocele Patient. Presented at the Joint Section of Pediatric Neurosurgeons, New Orleans, 1997.
Quigely MA, Cordes D, Arfanakis K, Meyerand ME, Iskandar B, Turski PA, Haughton VM: Comparison of activation maps prepared by ICA and by conventional methods in patients with focal lesions. 1999.
Iskandar BJ, Witwer B, Unlu A, Hariharan N, Javid M, Skene JHP: The role of fast axonal proteins in spinal cord regeneration. Society of Neuroscience. October 1999.
Risa T, Haughton V, Iskandar BJ, Turski P, Korosec F: Quantitation of cerebrospinal fluid in the foramen magnum in normal subjects and patients with Chiari malformations (submitted).
Iskandar BJ: New Observations in Syringomyelia.  Pan Arab Neurosurgical Society. October 2000.
Iskandar BJ: Spinal cord pulsations as a determinant of pathological pressure within a syrinx. AANS/CNS Joint Section of Pediatric Neurosurgery. December 2000.
Iskandar BJ: Folic acid supplementation enhances central nervous system regeneration. American Association of Neurological Surgeons. Toronto, April 2001.
Lapsiwala S, Rusy D, Medow J, Iskandar BJ: Intraoperative monitoring during tethered cord release in children.  Congress of Neurological Surgeons. October 2001.
Iskandar BJ, Resnick DK, Gao P, Skene JHP, Nelson A, Johnson C, Cechvala C & Hariharan N: Folic acid enhances regeneration and recovery from spinal cord injury. Society for Neuroscience, November 2001. 
Iskandar BJ, Resnick DK, Gao Peng, Skene JHP, Nelson A, Johnson C, Cechvala C & Hariharan N: Folic acid enhances regeneration and recovery from spinal cord injury. AANS/CNS Joint Section on Pediatric Neurosurgery, December 2001.
Dolar MTV, Haughton VM, Korosec FR, Medow JE, Iskandar BJ. Effect of suboccipital craniectomy on CSF flow velocity in patients with Chiari malformations. Annual Meeting of the American Society of Neuroradiology, Vancouver. May 13-17, 2002
V Haughton, M. Dolar, F Korosek, J Medow, B Iskandar Peak systolic CSF velocity in patients with Chiari malformations and in normal subjects. Western Neuroradiologic Society Meeting, Santa Barbara, CA, October 6 and 7, 2001
V Haughton, M. Dolar, F Korosek, M Quigley, B Iskandar Peak systolic CSF velocity in patients with Chiari malformations and in normal subjects. Nordic Neuroradiologic Society Meeting, Reyjkavik, June 2002
V Haughton, M. Dolar, F Korosek, M Quigley, B Iskandar Peak systolic CSF velocity in patients with Chiari malformations and in normal subjects. Symposium Neuroradiologicum, August 2002.
Quigley MF, Iskandar BJ, Mistretta CA, Haughton VM. Spatial and Temporal Characterization of CSF flow in the foramen magnum in normal subjects and patients with Chiari I malformations.
Puccetti D, Nguyen PH, Salamat S, Iskandar B and Norton L. Rapidly Growing Embryonal Carcinoma Arising in the Mesencephalon of a Young Child: A Case Report. 10th International Symposium of Paediatric Neuro-Oncology. June 2002.
Puccetti D, Iskandar B, Osenga K, and Schloegel D. False positive surveillance MR images in a young male with medulloblastoma Puccetti D, Iskandar B, Osenga K, and Schloegel D. 10th International Symposium of Paediatric Neuro-Oncology. June 2002.
Iskandar BJ, Nelson A, Gao P, Pawasarat J, Hariharan N.  The Effect of Folate Antagonists on CNS Regeneration.  JACS 195(3):S35, 2002.
Nelson A, Iskandar BJ. Folate Receptor Expression in CNS Injury and Regeneration. AANS/CNS Joint Section of Pediatric Neurosurgery, December 2002.
Medow J, Iskandar BJ. Quick-Brain MRI instead of CT in Shunted Hydrocephalus. AANS/CNS Joint Section of Pediatric Neurosurgery, December 2002.
Dziurzynski K, Iskandar BJ. Foramen Magnum Placement of Baclofen Pump Catheters. AANS/CNS Joint Section of Pediatric Neurosurgery, December 2002.
Medow J, Haughton V, Iskandar BJ. Elevation of peak systolic CSF velocity in patients with Chiari malformations compared to normal subjects. Congress of Neurological Surgeons, September 2002.
Iskandar BJ, Nelson A, Skene JHP, Gao P, Johnson C, Resnick DK, Hariharan N: Folic acid enhances repair mechanisms in the central nervous system. American Society of Pediatric Neurosurgeons, February 2003.
Iskandar BJ, Quigley M, Haughton V: Effect of posterior fossa decompression on CSF flow pattern in the foramen magnum of children with Chiari I malformations. American Association of Neurological Surgeons, April 2003.
Osenga K, Puccetti D, Iskandar BJ: Coagolopathies in childhood brain hemorrhages. Congress of Neurological Surgeons, October 2003.
Iskandar BJ, Dhodda VK, Unlu A, Vemuganti R, Hariharan N: The use of Genechip microarray analysis to differentiate between regeneration and injury signals in the injured adult mammalian CNS. Society of Neuroscience, November 2003.
Iskandar BJ, Nelson A, Resnick DK, Skene JHP, Gao P, Johnson C, Hariharan N: Folic acid enhances regeneration and recovery after central nervous system injury. Cervical Spine Research Society, December 2003.
Sansone J, Iskandar BJ. A novel approach to cerebral aqueductoplasty. AANS/CNS Section on Pediatric Neurological Surgery. December 2003.
Turk Q, Haughton V, Iskandar BJ, Quigley M. Effect of relative obstruction at the foramen magnum on CSF velocity: studies in an experimental model. ASNR 2004.
Sansone J, Mann D, Noonan K, McLeish D, Iskandar BJ: Rapid Progression of Scoliosis Following Insertion of Intrathecal Baclofen Pump (accepted, Pediatric Orthopedics meeting).
Iskandar BJ, Speer M: Familial relationship between Chiari I and Chiari 0. ASAP Conference, Miami 2004.
Hong TS, Puccetti D, Iskandar BJ, Salamat S, and Mehta MP. Combined Modality Therapy in the Management of Disseminated Primary Anaplastic Ependymoma of the Spinal Cord. Neurooncology Conference 2004.
Turk Q, Haughton V, Iskandar BJ, Quigley M. Effect of relative obstruction at the foramen magnum on CSF velocity: studies in an experimental model. ASNR 2004.
Haughton V, Iskandar BJ, Quigley M. CSF flow velocity in the foramen magnum of normal subjects in relation to age. ASNR 2004.
Moftakhar R, Speer M, Tubbs RS, Oakes WJ,  Iskandar BJ: Familial relationship between Chiari I and Chiari 0. AANS/CNS Pediatric Section, San Francisco, December 2004.
Rajpal S, Tubbs RS, George T, Oakes WJ, Hadley M, Iskandar BJ: Congenital tethered cord syndrome in adults (AANS, New Orleans, 2005).
Rizk E, Simon K, Jarrard D, Hariharan N, Iskandar BJ. The Role of DNA Methylation in Central Nervous System Regeneration (accepted to Neurotrauma Society, Washington DC, 2005).
Iskandar BJ. The role of DNA methylation in CNS regeneration (Neural Tube Defects meeting 2005).
Rajpal S, Tubbs S, Salamat S, Oakes WJ, Iskandar BJ.  Spinal cutaneous tracts in spina bifida occulta: Reclassification (AANS/CNS Section on Pediatric Neurosurgery, Orlando 2005).
Medow J, Iskandar BJ. Transcutaneous Inductive Pressure (TIP) Monitor: Prototype for a Permanently Implanted ICP Device (AANS/CNS Section on Pediatric Neurosurgery, Orlando 2005).
Iskandar BJ, Rizk E, Unlu A, Sun D, Vemuganti R, Turyen K, Hariharan N.  The Sodium Potassium ATPase Pump is essential in CNS regeneration (AANS/CNS Section on Pediatric Neurosurgery, Orlando 2005).
Moftakhar R, Salamat S, Iskandar BJ. Endoscopically-assisted resection of a choroid plexus vascular malformation traversing the cerebral aqueduct (AANS/CNS Section on Pediatric Neurosurgery, Orlando 2005).
Dziurzynski K, Iskandar BJ. The development of osmolar therapy at the University of Wisconsin (AANS/CNS Section on Pediatric Neurosurgery, Orlando 2005).
Rizk E, Simon K, Jarrard D, Hariharan N, Iskandar BJ. DNA methylation plays a significant role in folate-related CNS regeneration (AANS/CNS Section on Pediatric Neurosurgery, Orlando 2005).
Rizk E, Moftakhar R, Medow JE, Hariharan N, Iskandar BJ. Phenytoin decreases the ability of the CNS to repair after injury (accepted to Congress of Neurological Surgeons, Boston, 2005).
Iskandar BJ. The role of DNA methylation in CNS regeneration (American Academy of Neurological Surgeons, San Francisco Fall 2005; and Neurotrauma meeting Washington DC Fall 2005).
Iskandar BJ. Pediatric Neurosurgical Cases.  AANS Breakfast Seminar: Meet the Experts.  AANS. San Francisco. April 2006.
Iskandar BJ. Chiari I: Syndrome or Malformation.  AANS Breakfast Seminar: The Chiari Malformation.  AANS. San Francisco. April 2006.
Iskandar BJ. Accuracy of CSF flow imaging in the differentiation of symptomatic Chiari I malformation from asymptomatic incidental tonsilar ectopia. American SyringomyeliaAlliance Project. Denver. July 2006.
Iskandar BJ. The folate pathway, DNA methylation and CNS repair. FASEB. Palm Springs. August 2006.
Iskandar BJ. DNA Methylation and CNS Repair.  Society of Neuroscience. Atlanta. September 2006.
Rocque B, Lapsiwala S, Iskandar BJ. Shunt Tap as a Predictor of Proximal Shunt Function in Patients with Suspected Shunt Malfunction: a Prospective Study. AANS/CNS Section on Pediatric Neurosurgery, Denver. December 2006.
Rizk E, Iskandar BJ. The Folate Receptors in CNS Repair. AANS/CNS Section on Pediatric Neurosurgery, Denver. December 2006.
Rizk E, Iskandar BJ. The methyltransferases in CNS Regeneration after Injury.  AANS/CNS Pediatric Section. Miami. December 2007.
Meier B, Iskandar BJ. Nitrous Oxide Inhibits Neuronal Elongation in Culture. AANS/CNS Pediatric Section. Miami. December 2007.
Patel N, Iskandar BJ. The Association of Faint Midline Lumbar Cutaneous Hemangioma with Occult Spinal Dysraphism. AANS/CNS Pediatric Section. Miami. December 2007.
Iskandar BJ.  Understanding the Folate Pathway in CNS Repair. American Academy of Neurological Surgery. Las Vegas. October 2007.
Iskandar BJ.   The Role of the Folate Pathway in CNS Regeneration and Repair. NTD Research Meeting. Monterey. Septermber 2007
Patel N, Iskandar BJ: ICP Monitoring in patients with spasticity prior to Baclofen pump placement.  AANS/CNS Joint Section on Pediatric Neurosurgery. Washington. December 2008.
Stewart K, Iskandar BJ: The effect of folic acid on CNS regeneration in vitro. AANS/CNS Joint Section on Pediatric Neurosurgery. Washington. December 2008.
Rizk E, Iskandar BJ: Update on the The Folate Pathway and CNS Repair.  American Academy of Neurological Surgeons. September 2008 (presented in absentia by Dr. Rizk).
Rizk E, Iskandar BJ: The role of the NaK ATPase Pump in CNS regeneration. American Academy of Neurological Surgery. Arizona. September 2008 (presented by Dr. Rizk).
Martin BA, Labuda R, Royston TJ, Oshinski JN, Iskandar B, Loth F. Pathological biomechanics of cerebrospinal fluid pressure in syringomyelia:  Fluid structure interaction of an in vitro coaxial elastic tube system. ASME 2009 Summer Bioengineering Conference.
Iskandar BJ,  Banerjee R, Bottiglieri T, Finnell R, Hogan K.  The role of the folate pathway in repair of the injured central nervous system, NTD Conference, Burlington, Vermont, Septebmer 2009.
Iskandar BJ, Stewart K, Meier B, Rizk E, Hariharan N.  Folic Acid Supplementation Enhances CNS Regeneration in Vitro. American Academy of Neurological Surgery, West Palm Beach, Florida, October 2009.
Iskandar BJ, Patel N. Supplementing methyl donor groups in the Rat diet, increases neural regeneration after spinal cord injury.  AANS/CNS Joint Section on Pediatric Neurosurgery, Boston, Massachusetts, December 2009.
Patel NJ, Diamond CA, Salamat MS, Bradley K, Gondi V, Kennedy TA, Keller L, Iskandar BJ, Puccetti D.  A case of malignant rhabdoid tumor in the epidural space of the spine. J Neurooncology, 14th International Symposium on Pediatric Neuro-Oncology (ISPNO), Vienna, Austria, June 2010.
Patel NJ, Salamat MS, Puccetti DM, Gondi V, Bradley K, Keller L, Casey K, Kennedy TA, Iskandar BJ.  Primitive neuroectodermal tumor of the spine in a patient with a long lasting history of hydrocephalus. J Neurooncology , 14th International Symposium on Pediatric Neuro-Oncology (ISPNO), Vienna, Austria, June 2010.
Puccetti DM, Patel NJ, Iskandar BJ, Ward M, Casey K, Salamat MS, Kennedy TA. A child with disseminated primary spinal cord oligodendroglioma.  J Neurooncology, 14th International Symposium on Pediatric Neuro-Oncology (ISPNO), Vienna, Austria, June 2010.
Patel N, Puccetti D, Bradley K, Casey K, Keller L, Salamat S, Kennedy T, Iskandar MJ.  Primary primitive neuroectodermal tumor of the spine in a patient with a long lasting history of hydrocephalus. (Submitted), 14th International Symposium on Pediatric Neuro-Oncology (ISPNO), Vienna, Austria, June 2010.
Meier B, Stewart K, Iskandar BJ, Rizk E, Hogan K, et al. Nitrous Oxide Impairs Axonal Regeneration. (Submitted), American Society of Anesthesiologists Annual Meeting, San Diego, CA, October 2010.


Last update: September 2010