Curriculum Vitae
Julie K. Olson, Ph.D.
Department of Neurological Surgery
University of Wisconsin
School of Medicine and Public Health
Education:
Graduate:
1993-1998 The University of Iowa
College of Medicine
Iowa City, IA
Ph.D. in Microbiology
Thesis Advisor: Charles Grose, M.D
Undergraduate:
1989-1993 University of Wisconsin-La Crosse
La Crosse, WI
BS in Microbiology
Postdoctoral Fellow /Research Associate:
1998-2002 Northwestern University
The Feinberg School of Medicine
Department of Microbiology-Immunology
Chicago, IL
Sponsor: Stephen D. Miller, Ph.D.
Assistant Professor:
2005-present University of Wisconsin Medical School
Department of Neurological Surgery
Madison, WI
2003-2005 Northwestern University
The Feinberg School of Medicine
Department of Microbiology-Immunology
Chicago, IL
Research Grants:
National Multiple Sclerosis Society RG3625, 2005- current
National Multiple Sclerosis Society RG3629, 2002- 2007
Fellowship Grants:
NIH Ruth L. Kirschstein National Research Service Award (NRSA) for Postdoctoral Fellowship in Neurological Diseases NS10893, 1999-2002
Paralyzed Veterans of America Spinal Cord Research Foundation
Grant SCRF 2046, 1999-2001
NIH Postdoctoral Fellowship Training Grant, 1998-1999
Professional Experience:
NIH Ad Hoc Reviewer for NINDS NSD-B review panel 2007-
NIH Review panel ZAI1-HSD-I-M1: Innate Immunity and Viral Pathogenesis, 2006 -
NIH Review Panel DAIT-BAA-05-11: Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations, 2005
Awards:
American Association of Immunologists Junior Faculty Award 2009
American Association of Immunologists Junior Faculty Award 2006
Junior Faculty Award for Research Excellence,
Northwestern University 2004
Outstanding Neuroscience Research Fellow,
Northwestern University 2002
American Association of Immunologists Junior Scientist Award at the
International Congress on Immunology, Stockholm, Sweden 2002
Societies:
American Association for the Advancement of Science
American Association of Immunologists
Sigma Xi Professional Science Fraternity
Publications:
1. Thompson, E.A. and J.K. Olson. 2009. Effect of type I interferons on resident cells in the central nervous system. J. Neuroimmunol. Submitted.
2. Olson, J.K. 2009. IFNg promotes the innate immune response and protects from the development of autoimmune disease during Theiler’s virus infection. J. Immunol. Submitted.
3. Olson, J.K. 2009. Microglia in the spinal cord. Annals of N.Y. Acad. Sci. In Press.
4. Bowen, J.L. and J.K. Olson. 2009. Innate immune CD11b+Gr-1+ cells, suppressor cells, affect the immune response during Theiler’s virus- induced demyelinating disease. J. Immunol. In Press.
5. Olson, J.K. and S.D. Miller. 2009. The innate immune response affects the development of the autoimmune response in Theiler’s virus- induced demyelinating disease. J. Immunol.182:5712-5722.
6. Olson, J.K. and S.D. Miller. 2006. The role of T cells and the innate immune system in Theiler’s virus model of MS. Experimental Models of Multiple Sclerosis. ed. E. Lavi and C.S. Constantinescu. Springer Berlin Heidelberg New York.
7. Olson, J.K., J.L. Croxford, H.A. Anger, and S.D. Miller. 2005. Initiation and exacerbation of autoimmune demyelination of the central nervous system via virus-induced molecular mimicry: implications for the pathogenesis of multiple sclerosis. J. Virol. 79: 8581-90.
8. Olson, J.K., Ercolini A., and S.D. Miller. 2005. A virus-induced molecular mimicry model of multiple sclerosis. Curr Top Microbiol and Immunol. 296:39-53.
9. Carpentier, P.A., J.K. Olson, A. Elhofy, W.J. Karpus, and S.D. Miller. 2005. Differential activation of astrocytes by innate and adaptive immune stimuli. Glia. 49: 360-74.
10. Olson, J.K. and S.D. Miller. 2004. Activation through toll-like receptors leads to antigen presentation by microglia. J. Immunol. 15 :3916-24.
11. Olson, J.K., J.L. Croxford, and S.D. Miller. 2004. Innate and adaptive immune requirements for induction of autoimmune demyelinating disease by molecular mimicry. Mol. Immunol. 40: 1103-1108.
12. Fuller, K.G., J.K. Olson, L.M. Howard, J.L. Croxford, and S.D. Miller. 2004. Methods for induction and analysis of mouse models of multiple sclerosis: experimental autoimmune encephalomyelitis and Theiler’s virus-induced demyelinating disease. Autoimmunity: Methods and Protocols in Methods in Molecular Medicine. 102: 339-61.
13. Olson, J.K., L.J. Croxford, and S.D. Miller. 2003. Virus induced molecular mimicry in multiple sclerosis model. ASM News. 69: 432-37.
14. Olson, J.K., S.S. Zamvil, and S.D. Miller. 2003. Efficient technique for immortalization of murine microglial cells relevant for studies in murine models of multiple sclerosis. J. Neurosci. Meth. 128: 33-43.
15. Olson, J.K., T.N. Eagar, and S.D. Miller. 2002. Functional activation of myelin-specific T cells by virus-induced molecular mimicry. J. Immunol. 169:2719-2726.
16. Olson, J.K., L.J. Croxford, and S.D. Miller. 2002. Epitope spreading and molecular mimicry as triggers of autoimmunity in the Theiler's virus-induced demyelinating disease model of multiple sclerosis. Autoimmun Rev. 1(5):251-60.
17. Olson, J. K., L. J. Croxford, and S. D. Miller. 2001. Virus-induced autoimmunity: Potential role of viruses in initiation, perpetuation and progression of T cell-mediated autoimmune disease. Viral Immunol.14(3)227-250.
18. Olson, J. K., M. A. Calenoff, M. C. Dal Canto, and S. D. Miller. 2001. A virus-induced molecular mimicry model of multiple sclerosis. J. Clin. Invest. 108(2):311-318.
19. Rasley, A., J.K. Olson, K.L. Bost, S.D. Miller, and I. Marriott. 2001. Expression of functional NK-1 receptor in murine microglia. Glia 37(3):258-267
20. Olson, J. K., A. M. Girvin, and S. D. Miller. 2001. Direct activation of innate and antigen presenting functions of microglia following infection with Theiler’s virus. J. Virol. 75(20):9780-9789.
21. Begolka, W. S., L. M. Haynes, J. K. Olson, J. Padilla, K. L. Neville, M. C. Dal Canto, J. P. Palma, B. S. Kim, and S. D. Miller. 2001. CD8-deficient SJL mice display enhanced susceptibility to Theiler’s virus infection and increased demyelinating pathology. J. Neurovirol. 7(5):409-420.
22. Olson, J.K. and S.D. Miller. 2001. Myelin protein-specific CD4+ T cell response in virus-induced molecular mimicry model for multiple sclerosis. Scand. J. Immunol. 54 (Sup1): 63.
23. Miller, S. D., J. K. Olson, and L. J. Croxford. 2001. Multiple pathways to induction of virus-induced autoimmune demyelination: Lessons from Theiler’s virus infection. J. Autoimmunity. 16:219-227.
24. Katz-Levy, Y., K. L. Neville, J. Padilla, S. M. Rahbe, W. S. Begolka, A. M. Girvin, J.K. Olson, C. L. Vanderlugt, and S. D. Miller. 2000. Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler’s virus-infected mice. J. Immunol. 165:5304-5314.
25. Olson, J.K. and C. Grose. 1998. Varicella-zoster virus glycoprotein gE: endocytosis and trafficking of the Fc receptor. J. Infect. Dis. 178(Suppl 1):S2-6
26. Olson, J.K. and C. Grose. 1998. Complex formation facilitates endocytosis of the varicella-zoster virus gE:gI Fc receptor. J. Virol. 72:1542-1551.
27. Olson, J.K. and C. Grose. 1997. Endocytosis and recycling of varicella-zoster virus Fc receptor glycoprotein gE: internalization mediated by a YXXL motif in the cytoplasmic tail. J.Virol. 71: 4042-4054.
28. Olson, J.K., G.A. Bishop, and C. Grose. 1997. Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms. J. Virol. 71: 110-119.